Reports of shoulder dysfunction following inactivated influenza vaccine in the Vaccine Adverse Event Reporting System (VAERS), 2010- 2016

https://www.cdc.gov/vaccines/acip/meetings/downloads/slides-2017-10/vaccine-safety-03-shimabukuro-508.pdf

 

Background: shoulder
injury f
ollowing vaccination
1
Shoulder injury related to vaccine administration (SIRVA)
m
anifests as
shoulder pain and limited range of motion occurring after the
administration of a vaccine intended for intramuscular administration in
the upper
arm
These
s
ymptoms are thought to occur as a result of unintended injection
of vaccine antigen or trauma from the needle into and around the
underlying bursa of the shoulder resulting in an inflammatory
reaction
[B
y definition] SIRVA
is caused by an injury to the musculoskeletal
structures of the shoulder
(e.g. tendons, ligaments,
bursae
, etc
.)
SIRVA
i
s not a neurological injury
and abnormalities on neurological
examination or nerve conduction studies (NCS) and/or
electromyographic
(EMG) studies would not support SIRVA as a diagnosis (even if the
condition causing the neurological abnormality is not known)

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